
Buy Trittico (Trazodone) online. Free shipping. PayPal
Active ingredient: Trazodone.
Drug class: Antidepressant.
Other brand names: Desyrel, Desyrel Dividose, Oleptro.
Trittico is a new generation antidepressant with a mixed antagonistic and agonistic effect on serotonin metabolism. In addition, the drug belongs to a wide group of serotonin inhibitors. This effect on the structures of the central nervous system (CNS) makes Tritico one of the most effective treatments for depression. It is the most popular drug in the treatment of young patients.
Country of manufacture: Italy.
Manufacturer: Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F.
Form of release: Prolonged-release tablets, 150 mg, 20 pcs.
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Buy Trittico (Trazodone)
Trittico (Trazodone) is a drug that affects the emotional-volitional sphere of the psyche. It is prescribed for various depressive states and any symptomatic lowering of mood. The use of the remedy is justified in the following cases:
- Recurrent depressive disorder;
- A single depressive episode of mild to moderate severity;
- Old age depression;
- Mood depression due to any somatic pathology;
- Alzheimer's disease or discirculatory encephalopathy accompanied by depression and increased anxiety;
- Anxiety disorders (as a component of therapy);
- Chronic pain syndrome;
- Alcohol dependence that is accompanied by depression;
- Benzodiazepine tranquilizer withdrawal syndrome;
- Insomnia, including that caused by certain groups of psychotropic drugs (tricyclic antidepressants and selective serotonin reuptake inhibitors);
- Decreased sex drive, including during depression or after treatment with psychotropic drugs.
Tablets should be taken as a whole, without chewing, and with plenty of water.
Therapy should begin with evening doses and gradually increase daily doses.
The drug may be taken regardless of meals.How long should I take Trittico (Trazodone)?
The drug should be taken in cycles of at least one month.How should adults take Trittico (Trazodone)?
75-150 mg/day as a single dose in the evening before bedtime. The dose may be increased to 300 mg/day divided into two doses.
In hospitalized patients, the dose may be gradually increased to 600 mg/day in repeated doses.How should elderly patients take Trittico (Trazodone)?
In elderly or weakened patients, the recommended daily dose should be reduced to 100 mg/day as a fractional dose or as a single dose in the evening before bedtime.
This dose may be gradually increased under medical supervision depending on the efficacy and tolerability of the drug.
In most cases, a single dose of more than 100 mg should be avoided for these patients. A dose greater than 300 mg/day is not usually required.
How should children take Trittico (Trazodone)?
Children 6-18 years old: initial daily dose is 1.5-2 mg/kg/day divided into several doses. If necessary, the dose is gradually (at intervals of 3-4 days) increased to 6 mg/kg/day.
How to take Trittico (Trazodone) in case of libido disorders?
The recommended daily dose is 50 mg.
How to take Trittico (Trazodone) in case of erectile dysfunction?
monotherapy - recommended daily dose is 150-200 mg, combined therapy - 50 mg.
How to take Trittico (Trazodone) for alcoholism treatment?
The recommended treatment regimen is based on a gradual, sometimes over several months, reduction in the benzodiazepine dose. Each time the benzodiazepine dose is reduced by 1/4 or 1/2 tablet, 50 mg of trazodone is simultaneously added. This ratio is left unchanged for 3 weeks, and then a further gradual reduction in the dose of benzodiazepines is initiated until they are completely abolished. Thereafter, the daily trazodone dose is reduced by 50 mg every 3 weeks.
- hypersensitivity to trazodone or any excipient;
- alcohol intoxication and intoxication with sleeping pills;
- acute myocardial infarction;
- sucrose/isomaltose deficiency, fructose intolerance, glucose-galactose malabsorption, since the drug contains sucrose;
- age under 18 years (safety has not been established).
Careful
Cautious dosing and regular monitoring of patients with the following conditions is recommended:
- Epilepsy, especially abrupt increases or decreases in dose;
- patients with hepatic and/or renal insufficiency, especially severe;
- patients with heart disease, such as angina pectoris, conduction disorders or various degrees of atrioventricular (AV) block, myocardial infarction (early recovery period);
- hyperthyroidism;
- urinary disorders, such as prostatic hypertrophy, despite the minor anticholinergic effect of trazodone;
- acute closed-angle glaucoma, elevated intraocular pressure, although no serious changes are expected due to the minor anticholinergic effect of trazodone.
Can I take Trittico (Trazodone) during pregnancy?
Data from a limited number of pregnant women who took the drug during pregnancy (< 200) showed no adverse effects of trazodone on pregnancy and fetal/newborn health. No other available epidemiologic data are available.
The drug should be administered to pregnant women only if the potential benefit to the woman justifies the possible risks to the fetus. When used before delivery, neonates should be monitored for withdrawal syndrome.
Breastfeeding period
Limited data show that a small amount of trazodone passes into breast milk, but the level of the active metabolite is unknown. Due to insufficient data, the decision to continue/discontinue the drug or to continue/discontinue breastfeeding should be made taking into account the benefits of breastfeeding for the baby and the benefits of therapy for the mother.
When using Tritico, adverse reactions may occur in the brain, heart, hematopoietic organs, digestive system and sexual organs.
A frequent side effect is tremor, many patients also develop increased fatigue and somnolence, there may be headache. Rarely, on the contrary, unmotivated agitation occurs. Very rare CNS side effects include discoordination of movements and disorientation in space.
Trittico often causes decreased blood pressure and persistent hypotension, especially in persons prone to blood pressure fluctuations. In addition, supraventricular or ventricular blocks, other forms of brady and tachyarrhythmias may occur or worsen. From the side of the hematopoietic system, a decrease in hemoglobin, erythrocytes and leukocytes to the lower limit of normal or a mild degree of anemia and leukopenia often occurs.
A fairly rare side effect, in comparison with other antidepressants, is a decrease in appetite. Even rarer are dyspeptic disorders or transient bitterness in the mouth. Allergic reactions to the drug are also rare.
One of the most adverse side effects of triticale is priapism. Priapism is an erection unrelated to sexual arousal that causes pain and requires immediate treatment. This side effect is also rare.
Using the drug in doses exceeding the therapeutic ones increases the risk of adverse effects. The most common symptoms of triticale overdose are nausea, headache and drowsiness. Arterial hypotension, slow heart rate or ventricular tachyarrhythmias occur less frequently. In severe cases, overdose is accompanied by impairment of consciousness up to coma, seizures and respiratory failure of central genesis.
There is no specific antidote for triticale. In case of overdose, it is recommended to follow the same procedures as for any other poisoning. You should immediately call the ambulance station. Then - induce the patient's vomiting reflex, make an enema or give a laxative. If possible, it is necessary to flush the stomach. In severe cases, hospitalization in the intensive care unit is required.
One sustained-release tablet contains:
active substance: trazodone hydrochloride 150.0 mg;
excipients: sucrose (pressed sugar), carnauba wax, povidone K25 (polyvinylpyrrolidone), magnesium stearate.Here you can read a survey about Trazodone efficiency in cases with erectile dysfunction.
At a temperature not exceeding 25°C.
Keep out of reach of children.Shelf life: 3 years.
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Trazodone may increase the effect of some hypotensive drugs and usually requires reducing their doses.
Concomitant administration with CNS depressant drugs (including clonidine, methyldopa) enhances the effect of the latter.
Antihistamines and drugs with cholinolytic activity enhance the anticholinergic effect of trazodone.
Trazodone enhances and prolongs the sedative and anticholinergic effects of tricyclic antidepressants, haloperidol, loxapine, maprotiline, phenothiazine, pimozidan and tioxantine.
When concomitant administration of tricyclic antidepressants and trazodone, cardiovascular side effects may occur.
MAO inhibitors increase the risk of side effects.
Co-administration increases plasma concentrations of digoxin and phenytoin.
Studies of drug metabolism indicate the possibility of pharmacological interaction of trazodone with cytochrome P450 CYP3A4 inhibitors, such as ketoconazole, ritonavir, indinavir and fluoxetine. CYP3A4 inhibitors may lead to a significant increase in plasma concentration of trazodone, thereby increasing the likelihood of adverse events. Therefore, if taken in combination with potent CYP3A4 inhibitors, the dose of trazodone should be reduced.
When trazodone is taken in combination with carbamazepine, the plasma concentration of trazodone decreases. Therefore, patients taking trazodone and carbamazepine concomitantly should be closely monitored.
