The drug is taken orally, preferably 1 time / day in the evening before bedtime. Possible application 2 times / day - in the morning and evening before bedtime.
Adults: The effective daily dose is usually from 15 mg to 45 mg; the initial dose is 15 mg or 30 mg. A higher dose should be taken at night.
Treatment should be continued as far as possible until complete absence of symptoms within 4-6 months. After this, the drug can be gradually canceled.
Therapeutic effect is usually manifested after 1-2 weeks of treatment. Treatment with an adequate dose should result in a positive response in 2-4 weeks. If the response to treatment is insufficient, the dose can be increased to the maximum. In the absence of a therapeutic response, after 2-4 weeks treatment should be discontinued.
For elderly patients, the recommended dose is the same as for adults. In this category of patients, in order to achieve a satisfactory and safe response to treatment, an increase in the dose should be carried out under the direct supervision of a physician.
In patients with renal or hepatic insufficiency, it is possible to slow the excretion of mirtazapine from the body. This should be taken into account when prescribing a drug in this category of patients.
The tablets covered with a film cover, it is necessary to wash down with a liquid and to swallow without chewing.
The tablet for resorption should be put on the tongue and dissolve until it completely disintegrates. Tablets for resorption quickly destroyed in the language, for their intake does not require fluid. Before taking the drug and during its resorption, do not try to destroy the tablet (chew, break, etc.).
