Inside, with food.
Prevention of lactation: 1 mg once (2 tablespoons of 0.5 mg), on the first day after childbirth.
Suppression of steady lactation: 0.25 mg (1/2 table) 2 times a day every 12 hours for two days (total dose - 1 mg). In order to reduce the risk of orthostatic hypotension in breast-feeding mothers, a single dose of Dostinex® should not exceed 0.25 mg.
Treatment of violations associated with hyperprolactinemia: the recommended initial dose is 0.5 mg per week in a single dose (1 table to 0.5 mg) or in two divided doses (1/2 table 0.5 mg, for example, Monday and Thursday). The increase in the weekly dose should be carried out gradually - by 0.5 mg - with a monthly interval to achieve the optimal therapeutic effect. The therapeutic dose is usually 1 mg per week, but can range from 0.25 to 2 mg per week. The maximum dose for patients with hyperprolactinemia should not exceed 4.5 mg per week.
Depending on the tolerability, a weekly dose can be taken once or divided into 2 or more receptions per week. The division of a weekly dose into several doses is recommended when the drug is administered at a dose of more than 1 mg per week.
In patients with hypersensitivity to dopaminergic drugs, the likelihood of developing side effects can be reduced by initiating therapy with Dostinex® at a lower dose (eg, 0.25 mg once a week), then gradually increasing it until a therapeutic dose is reached. To improve the tolerability of the drug in the occurrence of severe side effects, a temporary dose reduction may be possible, followed by a more gradual increase (for example, an increase of 0.25 mg per week every 2 weeks).
