Buy Hyaluronidase online. PayPal
Active ingredient: Hyaluronidase.
Drug class: Enzymes and antienzymes.
Brand names: Hylenex, HyQvia, Vitrase, Liporaze, Hyalase, Hydase.
Hyaluronidase is an enzyme that breaks down hyaluronic acid into fragments, which are excreted from the body. It is contained in the connective tissues and contributes to the hyaluronic acid balance in the body. Hyaluronidase improves the permeability of tissues, skin elasticity, reduces swelling. Hyaluronidase great for skin rejuvenation!
Country of manufacture: Russia.
Form of release: One package contains 5 or 10 vials of lyophilizate 1280 IU for preparation of solution for intramuscular injection.
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Buy HYALURONIDASE
Hyaluronidase is used for:
- Removal of hyper-correction.
Excessive volume of injection gel can deprive the features of naturalness, distort them by migrating to neighboring areas. This problem is especially noticeable in the periorbital area, when Hyaluronic Acid is injected to smooth the "Crow's eyes", to eliminate dark circles under the eyes or nasolacrimal furrows. Instead of rejuvenation, the patient gets "edema" or swelling of the drug.
Hyaluronidase can either remove excess Hyaluronic Acid, or completely remove the entire filler - all depends on the wishes of the patient and the right dosage.
- Tindal effect.
If the hyaluronic filler is applied superficially or in excessive amounts, it, firstly, starts to protrude a noticeable bump and, secondly, to illuminate with a specific blue tint. This problem is called the Tindal effect and most often occurs when correcting the area under the eyes, where the skin is particularly thin and delicate.
- Granuloma Treatment.
Sometimes our body perceives the filler as an object hostile to it and turns on the "protective mode". During an immune reaction, a granuloma appears, a tumor-like formation that can be accompanied by inflammation symptoms. Hyaluronidase breaks down the hyaluronic acid polymer into short fragments that our immunity no longer perceives as hostile. The inflammatory process ends quickly and the thickening disappears.
- Prevention of necrosis.
The main symptoms are whitening of the skin in the injection area, its painfulness or numbness. The situation requires immediate injection of Hyaluronidase: it will destroy hyaluronic acid, restore blood flow and significantly reduce the area affected by necrosis. The main thing here is to hurry up, because the longer the time has passed since the beginning of ischemia, the more dangerous its consequences can be.
Hyaluronidase is also used in cases of:
- pneumofibrosis, tuberculosis, alveolitis;
- chronic interstitial cystitis;
- scars after pyodermia, injuries, burns, operations;
- long-lasting wounds that do not heal;
- joint contractures, arthritis, hematomas.
Hyaluronidase is injected in doses in those areas where the filler is located. Cosmetologists claim that 70% of success depends on preparatory measures.
How much hyaluronidase does it take to dissolve filler?
Ussualy an initial dose is 1500 IU of Hyaluronidase for 4 - 8 ml of saline solution.
It will be sufficient to use a minimum dose of the enzyme at maximum dilution to eliminate hyper-correction.
Stages of the procedure:
- How to make Hyaluronidase allergy test?
A drop of the preparation is applied to the wound in any part of the body. If no adverse reactions are observed, the drug can be used.
- Enzyme dilution in sterile solution.
In some cases, an anesthetic is added to the preparation.
- Acupuncture.
After another invasive intervention of Hyaluronidase, the skin may react with swelling and bruising. You should not be afraid of such manifestations, unless, of course, they are overdue for a week.
As in the case with the injection of filler, injections of enzymes may have side effects:
- an allergic reaction in the form of edema, itching and even anaphylactic shock;
- because of the wrong dose calculation, it is possible to dissolve the whole filler, although it was not necessary to remove it completely from the body;
- lack of effect, which is due to the parallel intake of antihistamines and hormones;
- the formation of asymmetry and new irregularities.
Hyaluronidase is a real lifesaver for cosmetologists. The drug has got low amount of contraindiactions, such as:
-
hypersensitivity;
-
acute infectious and inflammatory diseases;
- recent hemorrhages;
- acute intercourse diseases;
- children under 18 years of age.
-
Symptoms: chills, nausea, vomiting, dizziness, tachycardia, decreased BP, local edema, hives, erythema.
Treatment: administration of epinephrine; antihistamines.
Another theoretical risk from Hyaluronidase injections is the removal from the body not only filler, but also its own stock of hyaluronic acid. This may affect the quality of the skin (it becomes dryer), but after a while the level of HA is restored naturally.
In any case, experts believe that it is better to administer the drug in lower doses than in unnecessarily large ones. Experts advise to introduce very weak concentrations of the enzyme, breaking the correction into several stages. Thus, the procedure is more reliable and safe for the patient.
If the mesococktails included silicone, polymolactic acid or collagen, alas, there will be no result. That is why cosmetologists are very careful to introduce such fillers as Radiesse and Ellanse into the epidermis. If there are any errors in the procedure, it is very difficult to remove them.
Does Hyaluronidase dissolve your own tissue?
The largest number of fears on the forums is based on stories about how Hyaluronidase "eats" your own tissues, leaving on your face noticeable holes and failures. And, unfortunately, judging by the reviews, such defects hold for a very long time, sometimes for 1.5-2 years.
At the same time, many cosmeticians claim that Hyaluronidase is able to dissolve the tissues. And the consequences listed in the reviews of "victims" are either the manifestation of fibrous processes that form the edges of the "pit", or the results of experimental techniques, when to enhance the effect of hyaluronidase mixed with diprospan. These irregularities can be closed by means of secondary filler correction.
Does Hyaluronidase remove your own hyaluronic acid?
Another theoretical risk from Hyaluronidase injections is the removal from the body not only filler, but also its own stock of hyaluronic acid. This may affect the quality of the skin (it becomes dryer), but after a while the level of HA is restored naturally.
To reduce the risk of allergies, so that the correction does not turn into new problems, trust the procedure only to a professional cosmetologist who has practical experience in such work.
The decrease in the volume of previously introduced hyaluronic acid will be noticeable within 1-2 days. Often, the first effect is already visible 30 minutes after the procedure.
Control examination of the patient is carried out in 1-2 weeks, when swelling and swelling will completely disappear. If the result is still not enough, at this stage a little more enzyme is injected.
A new session of contour plastic surgery can be planned no earlier than 2-3 weeks later.
Indeed, for a long time hyaluronidase was used in the treatment of fibrous form of cellulite. For this purpose 1500 IU enzyme was diluted with 8-10 ml of physiological solution and injected deep under the skin (at the depth of not less than 1 cm) in the area of fibrosis. It was recommended to inject no more than 3000 IU of hyaluronidase during one procedure; the course of treatment included 1-2 procedures, which were conducted once a week. Currently, hyaluronidase drugs are rarely used in cellulite treatment, as more effective complex drugs have been developed, including adipolytic drugs based on sodium deoxycholate complex with phosphatidylcholine.
Early use of hyaluronidase drugs allows reducing fibrosis and post-traumatic edema after liposuction in the breast area (in gynecomastia in men) and in the submental area (the "second" chin). These procedures often lead to marked fibrosis, which is reduced very slowly, sometimes for several years. Timely injections of hyaluronidase can significantly reduce or completely eliminate postoperative fibrosis within a short period of time. A single application of 500 IU of hyaluronidase (1500 IU is diluted in 9 ml of physiological solution; 3 ml of solution is injected, fan-like) is enough to reduce fibrosis in the submental area. At the end of the procedure, a light massage is performed for better distribution of the preparation. And already during the massage it is possible to notice the reduction of fibrosis density.
For this purpose, doctors recommend using antihistamines, corticoids, adrenaline.
If the patient begins to fall sharply in pressure, it is best to use drugs that narrow blood vessels.
If an allergic reaction is slow, it can develop during the day. This can be manifested by the appearance of bubbles on the skin or redness with itching. They disappear on their own, and to prevent areas of irritation from scratching, they should be lubricated with corticosteroid gels and ointments.
Patients who are predisposed to allergies, it is necessary to conduct allergic tests. It is done as follows: Hyaluronidase dissolves in saline and is injected under the skin. If the puncture site begins to itch, the skin turns red and swollen, it means that the patient is allergic to the component.
In a dark place, at a temperature not exceeding 15°C.
Keep out of the reach of children.Shelf life: 2 years.
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