Buy Teraligen (Alimemazine). PayPal
Pharmacological group: antipsychotic.
Active ingredient: Alimemazine tartrate.
Other brand names: Theralene, Teralidzen.
Dosage form: tablets, solution for injection.
Release form: 25/50/100 tablets of 5 mg; 30 long-active tablets of 20 mg; 10 amp of 5 ml for injection per pack.
Teraligen (Alimemazine tartrate) is an antipsychotic agent (neuroleptic), has antihistamine, antispasmodic, serotonin blocking and moderate α-adrenergic blocking action, as well as antiemetic, hypnotic, sedative and antitussive action. Refers to aliphatic derivatives of phenothiazine.
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Buy Teraligen
Teraligen acts as a mild sedative and anti-anxiety agent, has a positive effect on senestopathy, obsession and phobia. It is used for psychosomatic manifestations that develop as a result of neurovegetative disorders, vascular, traumatic and infectious disorders of the central nervous system. The sedative effect contributes to the normalization of sleep in patients of this category. It has antiemetic and antitussive activity. Sedative and anxiolytic action is due to the blockade of adrenoreceptors of the reticular formation of the brain stem. The antiemetic and vegeto-stabilizing effect is due to the blockade of dopamine Ig receptors in the trigger zone of the vomiting center. Due to its antihistamine activity, alimemazine is used for allergic diseases, especially of the respiratory tract, and for pruritus. Alimemazine is more active in antihistaminic and sedative action than diprazine. The antipruritic effect is due to the effect on histamine receptors of the first type. Pharmacokinetics. Rapidly and completely absorbed by any route of administration.
The action of alimemazine begins 15-20 minutes after administration and lasts 6-8 hours. Communication with plasma proteins is 20-30%. Metabolized in the liver. Excreted by the kidneys - 70-80% as a metabolite (sulfoxide).
Broad-spectrum drug. Consult a specialist before use!
In adults and children from 7 years of age:
- As a sedative (calming), anxiolytic (anti-anxiety) and a sleep aid:
- dementia that occurs with manifestations of psychomotor agitation,
- organic anxiety disorder (in the form of monotherapy or as part of combination therapy);
- schizophrenia (with a predominance of neurosis-like disorders, as part of combination therapy);
- mood disorders (affective disorders) - as part of combination therapy;
- generalized anxiety disorder (as part of combination therapy);
- obsessive-compulsive disorder (as part of combination therapy);
- reaction to severe stress and adjustment disorders (acute reaction to stress, post-traumatic stress disorder, unspecified reaction to severe stress, other reactions to severe stress) - as part of combination therapy;
- dissociative (conversion) disorders (as part of combination therapy);
- somatoform disorders (somatization disorder, undifferentiated somatoform disorder, hypochondriacal disorder, somatoform dysfunction of the autonomic nervous system, persistent somatoform pain disorder, unspecified somatoform disorder, other somatoform disorders) - as part of combination therapy with severe anxiety or with the ineffectiveness of standard therapy;
- unspecified disorder of the autonomic (autonomic) nervous system, other disorders of the autonomic (autonomic) nervous system (as part of combination therapy);
- anorexia nervosa (as part of combination therapy);
- emotionally unstable personality disorder (impulsive and borderline types) - as part of combination therapy;
- hysterical personality disorder, anxious (avoidant, avoidant) personality disorder (as part of combined therapy);
- persistent personality change after experiencing a catastrophe (as part of combination therapy);
- hyperkinetic conduct disorder (as part of combination therapy);
- conduct disorder limited to the family (as part of combination therapy with the ineffectiveness of standard therapy);
- unsocialized conduct disorder (in the form of monotherapy or as part of combination therapy);
- anxiety, agitation and other symptoms and signs related to the emotional state (as part of combination therapy);
- other neurotic disorders (neurasthenia, unspecified neurotic disorder) - as part of combination therapy;
- insomnia of non-organic etiology (as part of combination therapy with the ineffectiveness of standard therapy);
- emotional disorders with onset specific to childhood (phobic anxiety disorder in childhood, social anxiety disorder in childhood, sibling rivalry disorder, unspecified emotional disorder in childhood, other emotional disorders in childhood) - as part of combination therapy.
As an antiallergic agent:
- itching regardless of location and etiology (itching of the anus, itching of the vulva, unspecified anogenital itching, itching with photocontact dermatitis and solar urticaria, dermatitis, eczema, urticaria, bites or stings by non-poisonous insects or other non-poisonous arthropods, chickenpox , measles, Hodgkin's disease, diabetes mellitus, herpes zoster) as monotherapy or as part of combination therapy;
- asthma, hay fever, whooping cough (as part of complex therapy as an antiallergic agent for coughing, shortness of breath and asthma attacks);
- unspecified allergy (in the form of monotherapy or as part of combination therapy).
In children from 3 years of age:
as an anti-allergic agent:
- itching, regardless of location and etiology (itching with photocontact dermatitis and solar urticaria, dermatitis, eczema, urticaria, bites or stings by non-poisonous insects or other non-poisonous arthropods, chicken pox, measles, Hodgkin's disease , diabetes mellitus, herpes zoster, anal itching, vulvar itching, unspecified anogenital itching) as monotherapy or as part of combination therapy.
As a sedative ( sedative) means:
- with medication preparation for surgery (for the purpose of sedation before surgery).
Side effects are rare and usually mild.
From the side of the nervous system:
- drowsiness,
- lethargy,
- fatigue (occur mainly in the first days of taking the drug and rarely require discontinuation of the drug),
- paradoxical reaction (anxiety, agitation, nightmares, irritability),
- confusion,
- extrapyramidal disorders (hypokinesia, akathisia, tremor).
From the senses:
- blurred vision (accommodation paresis),
- noise or ringing in the ears.
From the cardiovascular system:
- dizziness,
- lowering blood pressure (BP),
- tachycardia.
From the digestive system:
- dryness of the oral mucosa,
- atony of the gastrointestinal tract,
- constipation,
- loss of appetite.
From the respiratory system:
- dryness in the nose,
- pharynx,
- increased viscosity of bronchial secretions.
From the urinary system:
- bladder atony,
- urinary retention.
Other:
- allergic reactions,
- inhibition of bone marrow hematopoiesis,
- increased sweating,
- muscle relaxation,
- photosensitivity.
Contraindications:
- Hypersensitivity,
- angle-closure glaucoma,
- prostatic hyperplasia,
- severe liver and / or kidney failure, parkinsonism,
- myasthenia gravis,
- Reye's syndrome,
- simultaneous use of MAO inhibitors (including furazolidone, linezolid, etc.),
- pregnancy,
- lactation.
With caution:
- Alcoholism (history of complications with the use of phenothiazine drugs),
- bladder neck obstruction,
- predisposition to urinary retention,
- epilepsy,
- open-angle glaucoma,
- jaundice,
- bone marrow depression,
- arterial hypotension.
Tablets.
Inside. Without chewing. The effect of the drug is dose-dependent, doses are selected depending on the goals of therapy.
Adults.
- To achieve a vegetative-stabilizing effect, 15-60 mg / day.
- To achieve anxiolytic effect 20-80 mg/day.
- To achieve a sedative and / or hypnotic effect, 5-10 mg once (20-30 minutes before bedtime).
- For symptomatic treatment of allergic reactions 10-40 mg / day.
Course treatment should begin with taking 2.5-5 mg in the evening with a gradual increase in the daily dose to the desired effect. The daily dose can be divided into 3-4 doses. The duration of the course of treatment can be from 2 to 6 or more months and is determined by the doctor. The highest dose for adults is 500 mg / day, for the elderly (over 60 years old) - 200 mg / day.
Children from 7 years of age are prescribed according to the following scheme (depending on age and body weight).
- To achieve an anxiolytic effect 20-40 mg / day.
The course of treatment should begin with a dose of 2.5-5 mg with a gradual increase in the daily dose to the desired effect. The daily dose can be divided into 3-4 doses. To achieve a sedative and / or hypnotic effect, 2.5-5 mg once (20-30 minutes before bedtime).
- To achieve a sedative effect in violation of behavior in psychotic conditions, it is possible to increase the daily dose to 60 mg / day. For symptomatic treatment of allergic reactions 5-20 mg / day. The duration of the course of treatment can be from 2 to 6 months or more and is determined by the doctor.
Children from 3 years old.
- For symptomatic treatment of allergic reactions, 2.5-5 mg 3-4 times a day. The duration of the course of treatment can be from 2 to 6 or more months and is determined by the doctor.
- For the purpose of sedation before surgery, children from 3 to 7 years old are prescribed at the rate of 2 mg / kg 1-2 hours before surgery. The maximum daily dose is 2 mg/kg.
Solution for injection.
Apply intramuscularly, with care to avoid accidental subcutaneous injection, which can lead to local necrosis at the injection site. The dosage is determined by the doctor individually, depending on the nature of the disease. The maximum daily dose is 200 mg.
- Symptomatic treatment of allergic conditions - 25 mg 1-2 times a day. In acute cases and in psychiatric practice, adults are prescribed up to 100-200 mg / day.
- As a sedative during premedication - 25-50 mg 1-2 hours before surgery.
- In the complex therapy of alcohol withdrawal syndrome - 50 mg 1-2 times a day.
Enhances the effects of narcotic analgesics, hypnotics, anxiolytics (tranquilizers) and antipsychotic drugs (neuroleptics), as well as drugs for general anesthesia, m-anticholinergics and antihypertensive drugs (dose adjustment is required).
Weakens the action of amphetamine derivatives, m-cholinomimetics, ephedrine, guanethidine, levodopa, dopamine.
Combined use with ethanol and drugs that suppress the action of the central nervous system leads to increased depression of the central nervous system.
Antiepileptic drugs and barbiturates lower the seizure threshold (dose adjustment required). Beta-blockers increase (mutually) plasma concentration (possible pronounced decrease in blood pressure, arrhythmias).
Weakens the effect of bromocriptine and increases the concentration of prolactin in the blood serum.
Tricyclic antidepressants and anticholinergic drugs enhance m-anticholinergic activity.
MAO inhibitors (simultaneous administration is not recommended) and phenothiazine derivatives increase the risk of arterial hypotension and extrapyramidal disorders.
With the simultaneous appointment of alimemazine with drugs that inhibit bone marrow hematopoiesis, the risk of myelosuppression increases. Hepatotoxic drugs increase the manifestations of hepatotoxicity of the drug.
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You can legally buy Teraligen our website without prescription!
Alimemazine may mask the ototoxic effect (tinnitus, dizziness) of concomitantly used drugs. Alimemazine increases the body's need for riboflavin. To prevent distortion of the results of skin prick tests for allergens, the drug should be discontinued 72 hours before allergy testing. During treatment, false-positive results for pregnancy are possible. During treatment, you should not drink alcohol. Against the background of drug treatment, one should not engage in activities that require an increased concentration of attention and speed of psychomotor reactions (driving a car and other vehicles, working with moving mechanisms, the work of a dispatcher and operator).
With long-term treatment, it is necessary to systematically conduct a complete blood count, evaluate liver function. Increases the need for riboflavin. Solution for infusion contains inorganic sulfites, which can cause anaphylactic-type reactions.
