Buy Trichopol

Trichomoniasis, giardiasis, amebiasis (including amoebic liver abscess); infection (abdominal cavity, liver, pelvic organs, skin, bones, lower respiratory tract, central nervous system, sepsis, endocarditis) caused by anaerobic bacteria; mixed (aerobic and anaerobic) infections (in combination with antibiotics); infection Helicobacter pylori with peptic ulcer of the stomach or duodenum (in complex therapy with bismuth preparations and antibiotics), prevention of infections during surgical operations.

Inside, during or after a meal, without chewing.

Trichomoniasis
Adults and children over 10 years of age:
250 mg (1 tablet) 3 times a day or 500 mg (2 tablets) 2 times a day for 7 days. Women need to additionally appoint metronidazole in the form of vaginal suppositories or tablets. If necessary, you can repeat the course of treatment. Between the courses should be a break in 3 - 4 weeks with the conduct of repeated control laboratory tests.
An alternative regimen is the administration of 750 mg (3 tablets) in the morning and 1250 mg (5 tablets) in the evening or 2000 mg (8 tablets) as a single daily dose. Duration of treatment is 2 days.
Treatment is carried out at the same time for both sexual partners.
Children: from 3 to 7 years - 125 mg (1/2 tablets) 2 times a day; from 7 to 10 years - 125 mg (1/2 tablet) 3 times a day.
The course of treatment is 7 days.

Bacterial vaginosis
Adults:
For 500 mg (2 tablets) 2 times a day for 7 days or 2000 mg (8 tablets) as a single dose.
Simultaneous treatment of the sexual partner is not required.

Amebiasis
Invasive forms of intestinal amebiasis in susceptible patients (including amoebic dysentery)
Adults and children over 10 years of age:
For 750 mg (3 tablets) 3 times a day.
Children: from 3 to 7 years - 250 mg (1 tablet) 4 times a day; from 7 to 10 years - 375 mg (1.5 tablets) 3 times a day.
The course of treatment is usually 5 days.

Amoebiasis of the intestine in less susceptible patients and with chronic amoebic hepatitis Adults and children older than 10 years:
For 375 mg (1.5 tablets) 3 times a day.
Children: from 3 to 7 years - 125 mg (1/2 tablet) 4 times a day;
from 7 to 10 years - 250 mg (1 tablet) 3 times a day.
The duration of the course of treatment is 5 to 10 days.

Amoebic liver abscess and other forms of extraintestinal amebiasis
Adults and children over 10 years of age:
For 375 mg (1.5 tablets) 3 times a day.
Children: from 3 to 7 years - 125 mg (1/2 tablet) 4 times a day;
from 7 to 10 years - 250 mg (1 tablet) 3 times a day. The course of treatment is 5 days.

Asymptomatic carriage of cysts
Adults and children over 10 years of age:
For 375 - 750 mg (1.5 - 3 tablets) 3 times a day.
Children: from 3 to 7 years - 125 mg (1/2 tablet) 4 times a day;
from 7 to 10 years - 250 mg (1 tablet) 3 times a day.
The duration of the course of treatment is 5 to 10 days.

Lambliasis
Adults and children over 10 years of age:
For 500 mg (2 tablets) 2 times a day for 5-7 days;
or
By 2000 mg (8 tablets) once a day for 3 days.
Children: from 3 to 7 years - 250 - 375 mg (1 - 1.5 tablets) once a day for 5 days or 500 - 750 mg (2 - 3 tablets) once a day for 3 days; from 7 to 10 years - 250 mg (1 tablet) 2 times a day for 5 days
or
1000 mg (4 tablets) once a day for 3 days.

Infections of periodontal disease Acute ulcerative gingivitis
Adults and children over 10 years of age:
For 250 mg (1 tablet) 3 times a day.
Children: from 3 to 7 years - 125 mg (1/2 tablets) 2 times a day;
from 7 to 10 years - 125 mg (1 tablet) 3 times a day.
The duration of treatment is 3 days.

Acute odontogenic infections
Adults and children over 10 years of age:
For 250 mg (1 tablet) 3 times a day for 3 - 7 days.

Infections caused by anaerobic bacteria
Treatment of anaerobic infections usually begins with intravenous infusions. As soon as it becomes possible, the treatment should be continued with pills.
Adults and children older than 10 years: 500 mg (2 tablets) 3 - 4 times a day.
Children under the age of 10 years in the treatment of anaerobic infections recommend the use of infusion solutions metronidazole.
The duration of treatment should not exceed 7 days.

Eradication of Helicobacter pylori
For 500 mg (2 tablets) 3 times a day for 7 days (as part of combination therapy, for example, with amoxicillin 2.25 g per day).

Prevention of infections caused by anaerobic bacteria (before surgical operations on the abdominal cavity, in gynecology and obstetrics)
Adults and children over 12 years of age:
For 250 - 500 mg (1 - 2 tablets) 3 times a day for 3 - 4 days before surgery. After 1-2 days after the operation (when ingestion is already allowed), 250 mg (1 tablet) 3 times a day for 7 days.
With severe renal dysfunction (creatinine clearance less than 10 ml / min), the daily dose of metronidazole should be reduced 2-fold.

Metronidazole is a 5-nitroimidazole derivative with antiprotozoal and antibacterial action. The mechanism of action is the biochemical reduction of the 5-nitro group by intracellular transport proteins of anaerobic microorganisms and protozoa. The reduced 5-nitro group interacts with the DNA of a cell of microorganisms, inhibiting the synthesis of their nucleic acids, which leads to the death of bacteria.
Metronidazole is active against: Trichomonas vaginalis, Entamoeba histolyca, Gardnerella vaginalis, Giardia intestinalis, Lamblia spp., And obligate anaerobes Bacteroides spp. (including Bacteroides fragilis, Bacteroides distasonis, Bacteroides ovatus, Bacteroides thetaiotaomicron, Bacteroides vulgatus), Fusobacterium spp., Veillonella spp., Prevotella (Prevotella bivia, Prevotella buccae, Prevotella disiens) and some Gram-positive microorganisms (Eubacterium spp., Clostridium spp., Peptococcus spp., Peptostreptococcus spp.). The minimum inhibitory concentration (MIC) for these strains is 0.125-6.25 μg / ml. In combination with amoxicillin shows activity against Helicobacter pylori (amoxicillin suppresses the development of resistance to metronidazole).
Metronidazole has no bactericidal action against most aerobic bacteria and facultative anaerobes, fungi and viruses. In the presence of mixed flora (aerobes and anaerobes), metronidazole acts synergistically with antibiotics effective against conventional aerobes. Increases the sensitivity of tumors to radiation, causes sensitization to alcohol (disulfiram-like action), stimulates reparative processes.