Buy Paxil (Paroxetine) online. PayPal
Active ingredient: Paroxetine.
Pharmacological group: Antidepressant.
Other brand names:
Seroxat, Aropax, Brisdelle, Deroxat, Pexeva, Paxtine, Paxetin, Paroxat, Paraxyl, Sereupin, Daparox, Brisdelle.
Paxil (Paroxetine) is an antidepressant that is used to treat depression, obsessive-compulsive disorder (OCD), panic attacks, anxiety, or post-traumatic stress disorder (PTSD). Paroxetine helps many people recover from depression, and it has fewer side effects than other antidepressants.
Country of manufacture: Poland.
Manfacturer: GlaxoSmithKline Pharmaceuticals S.A.
Form of release: Tablets 20mg - 30 or 100 pcs. each.
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Buy Paxil (Paroxetine)
Paxil (Paroxetine) is prescribed in case of:
- Depression of all types in adults, including reactive depression, severe depression, and depression accompanied by anxiety;
- OCD in adults as well as children and adolescents 7-17 years old;
- panic disorder in adults, with and without agoraphobia;
- social phobia in adults, as well as in children and adolescents 8-17 years old;
- generalized anxiety disorder in adults;
- post-traumatic stress disorder in adults (including as a means of support and preventive therapy).
Also there is an evidence that Paxil may be effective for treatment of dysthymia, compulsive gambling and hot flashes.
In some cases Paxil can be good for treatment of diabetic neuropathy and chronic tension headache.
Inside (the tablet should be swallowed entirely, without chewing), 1 time a day (in the morning, with meals).
Depression
The recommended dose for adults is 20 mg/day, if necessary, depending on the therapeutic effect, the dose can be increased weekly by 10 mg/day to a maximum daily dose- 50 mg.
The use of Paxil for treatment of depression in children and adolescents (7-17 years) is not recommended due to the lack of data on the effectiveness of the therapy.
Obsessive-compulsive disorder (OCD)
The recommended dose for adults is 40 mg/day. Treatment begins with a dose of 20 mg per day, which can be increased weekly by 10 mg per day. If necessary, the dose may be increased to 60 mg/day.
Panic disorder
The recommended dose for adults is 40 mg/day. Treatment of patients should start with a dose of 10 mg/day and increase the weekly dose by 10 mg/day, focusing on the clinical effect. If necessary, the dose may be increased to 60 mg/day.
Social Phobia, Post-traumatic stress disorder and Generalized anxiety disorder
The recommended dose for adults is 20 mg/day. If necessary, the dose may be increased weekly by 10 mg/day depending on the clinical effect - up to 50 mg/day.
Depression
The use of Paxil in children and adolescents (7-17 years) for treatment of depression is not recommended due to lack of data on the effectiveness of the therapy.
Obsessive-compulsive disorder (OCD)
For children and adolescents (7-17 years old), the initial dose is 10 mg/day and can be increased by 10 mg/day weekly. If necessary, the dose can be increased to 50 mg/day.
Social Phobia
Treatment of children and adolescents (8-17 years old) should start with a dose of 10 mg/day and increase the dose by 10 mg/day weekly, focusing on the clinical effect. If necessary, the dose may be increased to 50 mg/day.
As soon as you feel better, you are likely to continue taking Paxil (Paroxetine) for several additional months to prevent symptoms from recurring. You should discuss the pros and cons of continuing to take Paxil with your doctor. The decision will depend on the type and severity of the symptoms, whether it is a single problem or not, how well paroxetine works for you, and whether you have had any side effects.
Paroxetine is safe to take for a long time. It seems that many months and years of taking the drug do not lead to any long-term harmful effects. However, taking paroxetine for more than one year was associated with a slight increased risk of diabetes.
The frequency and intensity of some of the following side-effects of paroxetine may decrease as the treatment continues, and such effects usually do not require withdrawal.
The side effects are stratified by organ systems and frequency. The frequency gradation is as follows: very often (≥1/10), often (≥1/100, <1/10), sometimes (≥1/1000, <1/100), rarely (≥1/10 000, <1/1000) and very rarely (<1/10 000), including individual cases.
Violations of the blood and lymphatic system:
Sometimes - abnormal bleeding, mainly bleeding into the skin and mucous membranes (most often bruises)
Very rarely - thrombocytopenia.
Violations by the immune system:
Very rarely - allergic reactions.
Endocrine disorders:
Very rarely - ADH syndrome (antidiuretic hormone).
Metabolic disorders:
Often - a decrease in appetite;
Rarely - hyponatremia (occurs mainly in elderly patients and may be due to ADH syndrome).
Mental disorders:
Often - sleepiness, insomnia;
Sometimes - confusion of consciousness, hallucinations;
Rarely - manic reactions.
These symptoms may also be due to the disease itself.
Visual disturbances:
Often - blurred vision;
Very rarely - exacerbation of glaucoma.
Violations of the heart:
Sometimes - sinus tachycardia.
Vascular disorders:
Sometimes - transitory increase or decrease in BP, including in patients with pre-existing arterial hypertension or anxiety.
Respiratory, chest and mediastinal disorders:
Often - yawning.
Violations of the nervous system:
Often - convulsive seizures.
Gastrointestinal disorders:
Very often - nausea;
Often - constipation, diarrhea, dry mouth;
Very rarely - gastrointestinal bleeding.
Hepatobiliary disorders:
Rarely - increase in liver enzymes level;
Very rarely - hepatitis, sometimes accompanied by jaundice and/or liver failure.
Violations of the skin and subcutaneous tissues:
Often - sweating;
Rarely - skin rashes;
Very rarely - photosensitivity reactions.
Violations of the kidneys and urinary tract:
Rarely - delayed urine.
Breakdowns from the reproductive system and mammary glands:
Very often - sexual dysfunction;
Rarely - hyperprolactinemia/galactorea.
General disorders:
Often - asthenia;
Very rarely - peripheral edema.
Symptoms arising from stopping treatment with paroxetine:
Often - dizziness, sensory disorders, sleep disorders, anxiety, headache;
Sometimes - agitation, nausea, tremor, confusion, sweating, diarrhea.
In most patients, these symptoms are mild to moderate and pass spontaneously.
Suicidal thoughts and suicidal attempts were mainly observed in clinical trials in adolescents with major depressive disorder, in which the efficacy of paroxetine has not been proven. Hostility was observed in children with OCD, especially those under 12 years of age.
- Hypersensitivity to Paroxetine and its components.
- Combined use of paraoxetine with MAO inhibitors (paraoxetine should not be used simultaneously with MAO inhibitors or within 2 weeks after their withdrawal; MAO inhibitors should not be prescribed within 2 weeks after cessation of treatment with paraoxetine).
- Combined use with thioridazine (paroxetine should not be used in combination with thioridazine, as like other drugs that inhibit the activity of CYP2D6 cytochrome P450 enzyme, paroxetine may increase thioridazine concentrations in plasma).
Available information on Paxil (Paroxetine) overdose indicates a wide range of its safety.
Symptoms: vomiting, dilation of the pupils, fever, changes in BP, involuntary contractions, agitation, anxiety, tachycardia.
The patient's condition usually normalized without serious consequences, even with a single dose of up to 2000 mg. A number of reports describe symptoms such as coma and ECG changes; deaths were very rare, usually in situations where patients were taking Paxil with other psychotropic drugs or alcohol.
Treatment: general measures applied in case of overdose of any antidepressants; if necessary - gastric lavage, prescription of activated carbon (20-30 mg every 4-6 hours during the first day after the overdose), maintenance therapy and frequent monitoring of basic physiological indicators.
If you sometimes forget to take a dose of paroxetine, do not worry. If you remember this before going to bed, then take Paxil immediately, if you remember at night or the next day, just forget about it.
Never take 2 doses at once to make up for the forgotten one.
You may not notice a significant improvement in your symptoms during the first two weeks until Paxil takes effect. It usually takes 4 to 6 weeks before you feel all the benefits. Do not stop taking paroxetine after a week or two just because you feel that it is not working. Give the medicine at least 6 weeks to work.
If you feel better for 6 months or more, your doctor may suggest you to give up paroxetine.
Your doctor will probably recommend a gradual dose reduction over a few weeks - or longer if you are taking paroxetine for a longer period of time.
This will help to prevent any additional side effects that may result from a reaction to your medication.
Do not stop taking Paxil suddenly or without talking to a doctor.
Active ingredient: hemhydrate 22.8 mg of paroxetine hydrochloride, which corresponds to 20 mg paroxetine content
Auxiliary substances: calcium dihydrophosphate dihydrate, type A sodium carboxyrichmal, magnesium stearate.
Shell composition: hypromellose, titanium dioxide, macrogol 400, polysorbate 80.At temperatures not exceeding 30 °C.
Keep out of the reach of children.Shelf life of Paxil: 3 years.
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